Portal de Periódicos da CAPES

Le site de référence du Partenariat européen d’innovation pour un vieillissement actif et en bonne santé MACVIA-LR (contre les maladies chroniques pour un vieillissement en bonne santé en Languedoc-Roussillon)

2015; Elsevier BV; Volume: 44; Linguagem: Inglês

10.1016/j.lpm.2015.07.013

2213-0276

Jean Bousquet, Rodolphe Bourret, Thierry Camuzat, Philippe Augé, Philippe Domy, J. Bringer, Nicolas Best, O. Jonquet, Jean-Emmanuel de La Coussaye, Michel Noguès, Jean‐Marie Robine, A. Avignon, Hubert Blain, Bernard Combe, Gérard Dray, Vincent Dufour, Mireille Fouletier, Nicolas Giraudeau, D. Hève, Claude Jeandel, Isabelle Laffont, Dominique Larrey, Daniel Laune, C. Laurent, P. Marès, Chantal Marion, E. Pastor, J Pélissier, F. Radier-Pontal, Jacques Reynes, E. Royère, Marc Ychou, Anna Bedbrook, Sophie A. Granier, Frédéric Abécassis, Sylvie Albert, P.A. Adnet, B. Alomène, Michel Amouyal, Sylvie Arnavieilhe, Trias Asteriou, V. Attalin, P Aubas, Christine Azevedo, Mélanie Badin, Karima Bakhti, Grégory Baptista, Benoît G. Bardy, M.-P. Battesti, Olivier Bénézet, Pierre Louis Bernard, Claudine Berr, J. Berthe, Xavier Bobia, Joël Bockaert, Catherine Boegner, Sylvie Boichot, Huei-Yune Bonnin, Philippe Boulet, Stéphane Bouly, C. Boubakri, Arnaud Bourdin, J.L. Bourrain, Gérard Bourrel, Vincent Bouix, Cyril Breuker, V. Bruguière, Jacques Burille, Stéphane Cade, Davide Caimmi, Marie-Virginie Calmels, William Camu, Gérard Canovas, V. Carre, Giacomo Cavalli, Guillaume Cayla, R. Chiron, P.-G. Claret, P. Coignard, F. Coroian, David Costa, Pierre Alves Costa, J. Cottalorda, Bertrand Coulet, Anne-Laure Coupet, Marie-Christine Courrouy-Michel, Philippe Courtet, Jean‐Paul Cristol, V. Cros, Frédéric Cuisinier, C. Daïen, Marianna Danko, P. Dauenhauer, M. Dauzat, Miren David, J M Davy, Didier Delignières, Pascal Demoly, M. Desplan, H. Dhivert‐Donnadieu, Pierre Dujol, Arnaud Dupeyron, G Dupeyron, Agnès Oude Engberink, M. Enjalbert, Charles Fattal, Jérôme Fernandes, Pierre Fesler, Philippe Fraisse, Jérôme Froger, Philippe Gabrion, E. Galano, M. Gellerat-Rogier, Anthony Gellis, Arnaud-Yves Goucham, Farès Gouzi, F. Gressard, Jean‐Christophe Gris, B. Guillot, David Guiraud, V. Handweiler, Olivier Hantkié, Maurice Hayot, C. Hérisson, C. Héroum, Didier Hoa, S. Jacquemin, Samir Jaber, Dominique Jakovenko, C. Jorgensen, Laurent Journot, Michel Kaczorek, Pascal Kouyoumdjïan, Pierre Labauge, Liliane Landreau, M. Lapierre, C. Leblond, Marie-Suzanne Léglise, Jean-Marc Lemaı̂tre, Vincent Le Moing, Alain Le Quellec, Françoise Leclercq, Sylvain Lehmann, Béatrice Lognos, J.-M. Lussert, Alain Makinson, Kévin Mandrick, V. Marmelat, P. Martin-Gousset, A. Matheron, G. Mathieu, Marc Meissonnier, Grégoire Mercier, Patrick Messner, Cyril Meunier, Michel Mondain, Raul Punta-Morales, Jacques Morel, David Morquin, Denis Mottet, Philippe Nérin, Pierre Nicolas, Grégory Ninot, Fabrice Nouvel, Jean-Paul Ortiz, Delphine Paccard, Guillaume Pandraud, M.-P. Pasdelou, Jean-Luc Pasquié, K. Patte, Stéphane Perrey, Yves‐Marie Pers, Marie‐Christine Picot, Jean‐Philippe Pin, Nathalie Pinto, Emilie Porte, F. Portejoie, Jean-Louis Pujol, Xavier Quantin, I. Quéré, N. Raffort, Sofiane Ramdani, Jean Ribstein, I. Rédini-Martinez, Sylvain Richard, Karen Ritchie, Jean-Pierre Riso, François Rivier, Christine Rolland, François Roubille, Denis Sablot, J.-L. Savy, L. Schifano, Pierre Sénesse, R. Sicard, B. Soua, Yannick Stéphan, D. Strubel, Ariane Sultan, Roxana Taddei-Ologeanu, G. Tallon, Michel Tanfin, Hervé Tassery, Isabel Tavares, Kjerstin Torre, Jacques Touchon, Vincent Tribout, Alain Uziel, Philippe Van de Perre, X. Vasquez, Jean‐Michel Verdier, Céline Vergne-Richard, Grégoire Vergotte, Laurence Vian, Christine Viarouge-Reunier, François Vialla, Frédéric Viart, Max Villain, Maxime Villiet, E. Viollet, Anne Wojtusciszyn, M. Aoustin, Christian Bourquin, Jacques Mercier,

Mitochondrial Function and Pathology

It is known that the removal of manganese from the water-oxidizing complex (WOC) of photosystem 2 (PS2) leads to activation of oxygen photoconsumption (OPC) [Khorobrykh et al., 2002; Yanykin et al., 2010] that is accompanied by the formation of organic hydroperoxides on the electron-donor side of PS2 [Khorobrykh et al., 2011]. In the present work the effect of trehalose on the OPC in Mn-depleted PS2 preparations (apo-WOC-PS2) was investigated. A more than two-fold increase of the OPC is revealed upon the addition of 1 M trehalose. Drastic (30%–70%) inhibition of the OPC upon the addition of either electron acceptor or electron donor indicates that the trehalose-induced activation of the OPC occurs on both donor and acceptor sides of PS2. A two-fold increase in the rate of superoxide-anion radical photoproduction on the electron-acceptor side of PS2 was also shown. Applying the "variable" chlorophyll fluorescence (ΔF) it was shown that the addition of trehalose induces: (i) a significant increase in the ability of exogenous Mn2 + to donate electrons to the reaction center of PS2, (ii) slowing down the photoaccumulation of the primary quinone electron acceptor of PS2 (QA−) under aerobic conditions, (iii) acceleration of the reoxidation of QA− by QB (and by QB−) as well as the replacement of QB2 − by a fully oxidized plastoquinone, and (iv) restoration of the electron transfer between the quinone electron carriers in the so-called "closed reaction centers of PS2" (their content in the apo-WOC-PS2 is 41%). It is suggested that the trehalose-induced increase in efficiency of the O2 interaction with the electron-donor and electron-acceptor sides of apo-WOC-PS2 is due to structural changes leading to both a decrease in the proportion of the "closed PS2 reaction centers" and an increase in the electron transfer rate in PS2.