Correlation of the Cell Surface Antigens with Stage and Grade in Cancer of the Bladder
1979; Lippincott Williams & Wilkins; Volume: 121; Issue: 1 Linguagem: Inglês
10.1016/s0022-5347(17)56650-1
ISSN1527-3792
AutoresR. Cameron Emmott, Nasser Javadpour, Stuart M. Bergman, T. Soares,
Tópico(s)Immunotherapy and Immune Responses
ResumoNo AccessJournal of Urology1 Jan 1979Correlation of the Cell Surface Antigens with Stage and Grade in Cancer of the Bladder R.C. Emmott, N. Javadpour, S.M. Bergman, and T. Soares R.C. EmmottR.C. Emmott More articles by this author , N. JavadpourN. Javadpour More articles by this author , S.M. BergmanS.M. Bergman More articles by this author , and T. SoaresT. Soares More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)56650-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Abstract: We examined 76 bladder tumors of various stages and grades for the presence of the ABO (H) cell surface antigen, using the specific red cell adherence technique. Of the grade I lesions studied 70 per cent were positive for the cell surface antigen and none of the 26 grade III tumors retained the antigens. When correlated with clinical stage the tumors showed no antigens for those of stages Bl to D, while 12 of 16 stage A lesions were positive for the antigen. When stage A lesions were studied and the findings were correlated with recurrence and metastasis/invasion ratesthe cell surface antigen was present on the initial tumor in only 1 lesion that recurred at an invasive stage. The findings of this study show that the specific red cell adherence technique may be valuable for predicting malignant potential in low grade, low stage cancer of the bladder. If supported by further investigation thistechnique may offer the capability of selecting low grade, low stage bladder tumors that are destined to invade or metastasize while they are at curable stages. © 1979 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byGhoneim M, El-Mekresh M, El-Baz M, El-Attar I and Ashamallah A (2018) Radical Cystectomy for Carcinoma of the Bladder: Critical Evaluation of the Results in 1,026 CasesJournal of Urology, VOL. 158, NO. 2, (393-399), Online publication date: 1-Aug-1997.Shaaban A, Tribukait B, El-Bedeiwy A and Ghoneim M (2018) Characterization of Squamous Cell Bladder Tumors by Flow Cytometric Deoxyribonucleic Acid Analysis: A Report of 100 CasesJournal of Urology, VOL. 144, NO. 4, (879-883), Online publication date: 1-Oct-1990.Sheinfeld J, Reuter V, Melamed M, Fair W, Morse M, Sogani P, Herr H, Whitmore W and Cordon-Cardo C (2018) Enhanced Bladder Cancer Detection with the Lewis X Antigen as a Marker of Neoplastic TransformationJournal of Urology, VOL. 143, NO. 2, (285-288), Online publication date: 1-Feb-1990.Walton G, McCue P and Graham S (2018) Beta-2-Microglobulins as a Differentiation Marker in Bladder CancerJournal of Urology, VOL. 136, NO. 6, (1197-1200), Online publication date: 1-Dec-1986.Das G, Buxton N, Hamilton Stewart P and Glashan R (2018) Prognostic Significance of ABH Antigenicity of Mucosal Biopsies in Superficial Bladder CancerJournal of Urology, VOL. 136, NO. 6, (1194-1196), Online publication date: 1-Dec-1986.Cuadrado E, Rodriguez-Trinidad A, Blasco E, Torrado J, Lopez Garcia J and Arozena F (2018) Blood Group Isoantigens ABO (H) in Transitional Carcinoma of the Bladder: A Clinicopathological StudyJournal of Urology, VOL. 135, NO. 2, (409-415), Online publication date: 1-Feb-1986.Borgström E and Wahren B (2018) Quantitative Analysis of the A, B and H Isoantigens in Single Transitional Carcinoma CellsJournal of Urology, VOL. 134, NO. 1, (199-202), Online publication date: 1-Jul-1985.Seal G, Rowland R, Thomalla J, Rudolph R, Pfaff D, Kamer M and Eble J (2018) A, B and H Antigens in Normal Urothelium: An Immunohistochemical Study Using Monoclonal Antibodies with the Avidin-Biotin Complex TechniqueJournal of Urology, VOL. 133, NO. 3, (513-516), Online publication date: 1-Mar-1985.Lange P and Limas C (2018) Editorial CommentJournal of Urology, VOL. 131, NO. 2, (250-251), Online publication date: 1-Feb-1984.El Adl M, Yamase H, Nieh P, Mostofa A, Hinz C and Walzak M (2018) ABH Cell Surface Isoantigens in Invasive Bladder Carcinoma Associated With SchistosomiasisJournal of Urology, VOL. 131, NO. 2, (249-250), Online publication date: 1-Feb-1984.Catalona W (2018) Editorial CommentJournal of Urology, VOL. 130, NO. 5, (873-873), Online publication date: 1-Nov-1983.King C, Clark T, Lovett J, Cash J, Primus F, McRoberts J and Flanigan R (2018) A Comparison of Clinical Course with Blood Group Antigen Testing by Specific Red Cell Adherence and Immunoperoxidase in Ureteral and Renal Pelvic TumorsJournal of Urology, VOL. 130, NO. 5, (871-873), Online publication date: 1-Nov-1983.Catalona W (2018) Editorial CommentJournal of Urology, VOL. 130, NO. 3, (503-503), Online publication date: 1-Sep-1983.Flanigan R, King C, Clark T, Cash J, Jane Greenfield B, Sniecinski I and James Primus F (2018) Immunohistochemical Demonstration of Blood Group Antigens in Neoplastic and Normal Human Urothelium: A Comparison with Standard Red Cell AdherenceJournal of Urology, VOL. 130, NO. 3, (499-503), Online publication date: 1-Sep-1983.Catalona W (2018) Editorial CommentJournal of Urology, VOL. 130, NO. 1, (73-73), Online publication date: 1-Jul-1983.Wolk F and Bishop M (2018) The Specific Red Cell Adherence Test in Transitional Cell Carcinoma of the Bladder Before and After Radiotherapy in Patients With Blood Group AJournal of Urology, VOL. 130, NO. 1, (71-73), Online publication date: 1-Jul-1983. (2018) Reply by AuthorsJournal of Urology, VOL. 130, NO. 1, (69-70), Online publication date: 1-Jul-1983.Lange P and Limas C (2018) Editorial CommentsJournal of Urology, VOL. 130, NO. 1, (69-69), Online publication date: 1-Jul-1983.Richie J (2018) Editorial CommentsJournal of Urology, VOL. 130, NO. 1, (69-69), Online publication date: 1-Jul-1983.Vallancien G, Rouger P, LeClerc J and Kuss R (2018) Immunofluorescence Study of the Distribution of A, B and H cell surface Antigens in Bladder TumorsJournal of Urology, VOL. 130, NO. 1, (67-69), Online publication date: 1-Jul-1983.Javadpour N (2018) Cell Surface Antigens in Bladder CancerJournal of Urology, VOL. 129, NO. 2, (439-439), Online publication date: 1-Feb-1983.Catalona W (2018) Editorial CommentJournal of Urology, VOL. 128, NO. 6, (1189-1189), Online publication date: 1-Dec-1982.Ghazizadeh M, Kagawa S and Kurokawa K (2018) Specific Red Cell Adherence Testing of Benign and Malignant Lesions of the UrethraJournal of Urology, VOL. 128, NO. 6, (1188-1189), Online publication date: 1-Dec-1982.Hammou J, Fella C, Vacant J, Maiolini R and Masseyeff R (2018) Improvement of the Demonstration of A, B, H Surface Antigens in Bladder Tumors by a Simple Immunofluorescence TechniqueJournal of Urology, VOL. 128, NO. 6, (1183-1187), Online publication date: 1-Dec-1982.Droller M (2018) Editorial CommentJournal of Urology, VOL. 127, NO. 4, (666-667), Online publication date: 1-Apr-1982.D’Elia F, Cooper H and Grant Mulholland S (2018) ABH Isoantigens in Stage O Papillary Transitional Cell Carcinoma of the Bladder: Correlation with Biological BehaviorJournal of Urology, VOL. 127, NO. 4, (665-666), Online publication date: 1-Apr-1982.Soloway M (2018) Editorial CommentJournal of Urology, VOL. 126, NO. 1, (40-40), Online publication date: 1-Jul-1981.Stein B, Reyes J, Petersen R, McNellis D and Kendall A (2018) Specific Red Cell Adherence: Immunologic Evaluation of Random Mucosal biopsies In Carcinoma of the BladderJournal of Urology, VOL. 126, NO. 1, (37-40), Online publication date: 1-Jul-1981.Coon J and Weinstein R (2018) Variability in the Expression of the O(H) Antigen in Human Transitional EpitheliumJournal of Urology, VOL. 125, NO. 3, (301-306), Online publication date: 1-Mar-1981.Emmott R, Droller M and Javadpour N (2018) Studies of A, B or O (H) Surface Antigen Specificity: Carcinoma in Situ and Non-Malignant Lesions of the BladderJournal of Urology, VOL. 125, NO. 1, (32-35), Online publication date: 1-Jan-1981.Lange P and Limas C (2018) Tissue Blood Group Antigen Testing in Transitional Cell Carcinoma of the BladderJournal of Urology, VOL. 124, NO. 2, (304-304), Online publication date: 1-Aug-1980.Ramsey E (2018) Specific Red Cell Adherence TechniqueJournal of Urology, VOL. 124, NO. 2, (304-304), Online publication date: 1-Aug-1980.Newman A, Carlton C and Johnson S (2018) Cell Surface A, B or O(H) Blood Group Antigens as an Indicator of Malignant Potential in Stage A Bladder CarcinomaJournal of Urology, VOL. 124, NO. 1, (27-29), Online publication date: 1-Jul-1980. (2018) Reply by AuthorsJournal of Urology, VOL. 123, NO. 1, (28-28), Online publication date: 1-Jan-1980.Droller M (2018) Editorial CommentJournal of Urology, VOL. 123, NO. 1, (28-28), Online publication date: 1-Jan-1980.Johnson J and Lamm D (2018) Prediction of Bladder Tumor Invasion with the Mixed Cell Agglutination TestJournal of Urology, VOL. 123, NO. 1, (25-28), Online publication date: 1-Jan-1980. Volume 121Issue 1January 1979Page: 37-39 Advertisement Copyright & Permissions© 1979 by The American Urological Association Education and Research, Inc.MetricsAuthor Information R.C. Emmott More articles by this author N. Javadpour More articles by this author S.M. Bergman More articles by this author T. Soares More articles by this author Expand All Advertisement PDF downloadLoading ...
Referência(s)