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A 52-year-old woman with a subcutaneous, slightly movable and painless nodule in the left breast

2006; King Faisal Specialist Hospital and Research Centre; Volume: 26; Issue: 5 Linguagem: Inglês

10.5144/0256-4947.2006.403

0975-4466

Joško Bežić, Branka Vrbičić, Paško Guberina, Vinko Alfier, Petar Projić, Zlatko Marović,

Breast Cancer Treatment Studies

What’s your diagnosis?A 52-year-old woman with a subcutaneous, slightly movable and painless nodule in the left breast Joško Bezić, Branka Vrbičić, Paško Guberina, Vinko Alfier, Petar Projić, and Zlatko Marović Joško Bezić Department of Pathology, Clinical Hospital Split, Croatia Search for more papers by this author , Branka Vrbičić Department of Pathology, Regional Hospital Šibenik, Croatia Search for more papers by this author , Paško Guberina Department of Radiology, Regional Hospital Šibenik, Croatia Search for more papers by this author , Vinko Alfier Department of Surgery, Regional Hospital Šibenik, Croatia Search for more papers by this author , Petar Projić Department of Pathology, Clinical Hospital Split, Croatia Search for more papers by this author , and Zlatko Marović Medical School, University of Split, Croatia Search for more papers by this author Published Online:5 Oct 2006https://doi.org/10.5144/0256-4947.2006.403SectionsPDF ToolsAdd to favoritesDownload citationTrack citations ShareShare onFacebookTwitterLinked InRedditEmail AboutIntroductionA 52-year-old woman from Šibenik, Southern Croatia, presented in March 2004 to her clinician with the subcutaneous, slightly movable and painless nodule in the left breast, noticed one month before. The rest of clinical examination was normal and laboratory findings were within normal limits without eosinophilia. She had not travelled abroad in recent years.Left breast mammography was normal while an ultrasonographic examination showed an oval, well circumscribed hypoechogenic structure measuring 16×4 mm, located in subcutaneous tissue (Figure 1). The initial diagnosis was inflamed atheroma, and surgical excision of the nodule was performed. On gross examination the specimen was a nodular subcutaneous mass of 1.6 cm in greatest diameter, with a soft yellow-white cut surface. The histological slides were stained with haematoxylin and eosin. Histologically, the nodule was composed of a suppurative centre with a few transverse sections of structure surrounded by a granulomatous inflammatory infiltrate composed of histiocytes admixed with polymorphous leucocytes and lymphocytes (Figures 2, 3).Figure 1 Ultrasonographic picture of the well-circumscribed, hypoechogenic subcutaneous breast structure.Download FigureFigure 2 Transverse section of the subcutaneous structure, surrounded by a granulomatous inflammatory reaction (H&E section, × 40).Download FigureFigure 3 Transverse section of the subcutaneous structure (H&E section, × 200).Download FigureWhat is the structure seen in the histological slides?What is the diagnosis?Answers on page 414. Previous article Next article FiguresReferencesRelatedDetails Volume 26, Issue 5September-October 2006 Metrics History Published online5 October 2006 InformationCopyright © 2006, Annals of Saudi MedicineThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.PDF download