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Approach to asymptomatic creatine kinase elevation

2016; Cleveland Clinic; Volume: 83; Issue: 1 Linguagem: Inglês

10.3949/ccjm.83a.14120

1939-2869

Siamak Moghadam‐Kia, Chester V. Oddis, Rohit Aggarwal,

Drug-Induced Ocular Toxicity

How to manage a patient who has an elevated serum creatine kinase (CK) level but no or insignificant muscle-related signs and symptoms is a clinical conundrum. The authors provide a systematic approach, including repeat testing after a period of rest, defining higher thresholds over which pursuing a diagnosis is worthwhile, and evaluating for a variety of nonneuromuscular causes. They also outline a workup for neuromuscular causes.