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Intraoperative Nutzung eines offenen Mittelfeld-MRT während der chirurgischen Therapie zerebraler Gliome

2003; Elsevier BV; Volume: 13; Issue: 3 Linguagem: Inglês

10.1078/0939-3889-00167

1876-4436

Jens‐Peter Schneider, C. Trantakis, Thomas Schulz, Jürgen Dietrich, Thomas Kahn,

Medical Imaging Techniques and Applications

The aim of the present study was to evaluate the effectiveness of intraoperative MRI guidance in achieving more gross-total resection in case of primary brain tumors. We studied 12 patients with low-grade glioma and 19 patients with high-grade glioma who underwent surgery within a vertically open 0.5 T MR system. After initial imaging, the resection was stopped at the point in which the neurosurgeon considered the resection complete by viewing the operation field. At this time, intraoperative MRI was repeated ("first control") to identify any residual tumor. Areas of tumor-suspected tissue were localized and resected, with the exception of tissue adjacent to eloquent areas. Final imaging was carried out before closing the craniotomy. Comparison of "first control" and final imaging revealed a decrease of residual tumor volume from 32% to 4.3% in low-grade gliomas, and from 29% to 10% in high-grade gliomas. Intraoperative MRI allows a clear optimization of microsurgical resection of both low-grade and high-grade gliomas.