Produção Nacional
Serum cholinesterase polymorphism (CHE1 and CHE2 loci) among several Indian groups from Amazon region of Brazil, and segregation of the C5 variant in families.
1989; Tor Vergata University of Rome; Volume: 3; Issue: 1 Linguagem: Inglês
ISSN
0394-249X
AutoresGuerreiro JF, Santos Se, Aguiar Gf,
Tópico(s)Insect Resistance and Genetics
ResumoEight Indian tribes from the Amazon region of Brazil (Arawete, Arara, Yamamadi, Kararao, Karitiana, Waiampi, Surui and Cinta Larga) were studied for the distribution of the atypical and C5 variants of serum cholinesterase. None of them presented the CHE1*A allele, but the C5 variant was found in the Arawete (20.4%), Kararao (15.6%), Karitiana (50.5%), Surui (12.3%) and Cinta Larga (19.6%) tribes. The frequency of the C5+ phenotype in the Karitiana is the highest reported thus far in human populations. Segregation studies considering the C5 variant were made among the Karitiana, and also among the Urubu-Kaapor and Munduruku tribes previously studied by Guerreiro et al [1987a, 1987b]. Most of the data were in agreement with the genetic hypothesis, but they also revealed a significant lack of the C5+ phenotype in offspring from C5+ X C5+ matings, as well as the occurrence of two C5+ children from C5- X C5- unions, in the Urubu-Kaapor tribe.
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