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Histologic Grading of Primary Prostatic Cancer: A New Approach to an Old Problem

1980; Lippincott Williams & Wilkins; Volume: 123; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(17)56093-0

1527-3792

John F. Gaeta, John E. Asirwatham, Gary J. Miller, Gerald P. Murphy,

Bladder and Urothelial Cancer Treatments

No AccessJournal of Urology1 May 1980Histologic Grading of Primary Prostatic Cancer: A New Approach to an Old Problem John F. Gaeta, John E. Asirwatham, Gary Miller, and Gerald P. Murphy John F. GaetaJohn F. Gaeta More articles by this author , John E. AsirwathamJohn E. Asirwatham More articles by this author , Gary MillerGary Miller More articles by this author , and Gerald P. MurphyGerald P. Murphy More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)56093-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail A simple and objective system for grading prostatic carcinoma was evaluated in a retrospective analysis of 169 cases followed during a 16-year period. The system identified and separated 4 grades of increasing malignancy based on the combined evaluation of gland differentiation and nuclear anaplasia as separate but complementary factors. The system demonstrates significant correlation with mortality rates for each grade group. Retrospective evaluation of the extent of the disease at the time of initial diagnosis also indicates correlation between prostatic grades and clinical stages. © 1980 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited BySchäfer W, Funke P, Kunde D, Rausch U, Wennemuth G and Stützer H (2018) Intensity of Androgen and Epidermal Growth Factor Receptor Immunoreactivity in Samples of Radical Prostatectomy as Prognostic Indicator: Correlation With Clinical Data of Long-Term ObservationsJournal of Urology, VOL. 176, NO. 2, (532-537), Online publication date: 1-Aug-2006.ZHOU M, HAYASAKA S, TAYLOR J, SHAH R, PROVERBS-SINGH T, MANLEY S and RUBIN M (2018) LACK OF ASSOCIATION OF PROSTATE CARCINOMA NUCLEAR GRADING WITH PROSTATE SPECIFIC ANTIGEN RECURRENCE AFTER RADICAL PROSTATECTOMYJournal of Urology, VOL. 166, NO. 6, (2193-2197), Online publication date: 1-Dec-2001.Fowler J, Terrell F and Renfroe L (2018) Co-Morbidities and Survival of Men with 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Prediction of Metastatic Potential by a New Grading System of Cell Motility: Validation in the Dunning R-3327 Prostatic Adenocarcinoma ModelJournal of Urology, VOL. 138, NO. 1, (168-170), Online publication date: 1-Jul-1987.Gibbons R, Cole B, Richardson R, Correa R, Brannen G, Mason J, Taylor W and Hafermann M (2018) Adjuvant Radiotherapy Following Radical Prostatectomy: Results and ComplicationsJournal of Urology, VOL. 135, NO. 1, (65-68), Online publication date: 1-Jan-1986.Gibbons R, Correa R, Brannen G and Mason J (2018) Total Prostatectomy for Localized Prostatic CancerJournal of Urology, VOL. 131, NO. 1, (73-76), Online publication date: 1-Jan-1984.Thomas R, Lewis R, Sarma D, Coker G, Rao M and Roberts J (2018) Aid to Accurate Clinical Staging—Histopathologic Grading in Prostatic CancerJournal of Urology, VOL. 128, NO. 4, (726-728), Online publication date: 1-Oct-1982.Eggleston J (2018) Editorial CommentJournal of Urology, VOL. 128, NO. 4, (728-728), Online publication date: 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Volume 123Issue 5May 1980Page: 689-693 Advertisement Copyright & Permissions© 1980 by The American Urological Association Education and Research, Inc.MetricsAuthor Information John F. Gaeta More articles by this author John E. Asirwatham More articles by this author Gary Miller More articles by this author Gerald P. Murphy More articles by this author Expand All Advertisement PDF DownloadLoading ...