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Hemodynamic Effect of the Metallopurpurin Snet2 and Light on Transplantable Fanft Induced Bladder Tumor

1990; Lippincott Williams & Wilkins; Volume: 143; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)40044-9

1527-3792

Steven H. Selman, Binsheng Qin, Harold R. James, Rick W. Keck, Greta M. Garbo, Alan R. Morgan,

Cancer, Hypoxia, and Metabolism

No AccessJournal of Urology1 Mar 1990Hemodynamic Effect of the Metallopurpurin Snet2 and Light on Transplantable Fanft Induced Bladder Tumor Steven H. Selman, Binsheng Qin, Harold R. James, Rick W. Keck, Greta M. Garbo, and Alan R. Morgan Steven H. SelmanSteven H. Selman More articles by this author , Binsheng QinBinsheng Qin More articles by this author , Harold R. JamesHarold R. James More articles by this author , Rick W. KeckRick W. Keck More articles by this author , Greta M. GarboGreta M. Garbo More articles by this author , and Alan R. MorganAlan R. Morgan More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)40044-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Changes in blood flow to transplantable N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide induced bladder tumors growing subcutaneously in the flanks of Fischer CDF (F344/CrlBR) rats were measured after photodynamic therapy with the photosensitizer tin (II) etiopurpurin dichloride using the radioactive microsphere technique. As with the other photosensitizers, hematoporphyrin derivative and chloroaluminum tetrasulfophtalocyanine, tin (II) etiopurpurin dichloride and light caused a rapid decrease in tumor blood flow in this tumor model. The decrease in blood flow occurred whether the vehicle for photosensitizer delivery was an emulsion or a liposome. Systemic heparinization of animals prior to light treatment did not alter changes in tumor blood flow. © 1990 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited bySelman S and Keck R (2018) The Effect of Transurethral Light on the Canine Prostate after Sensitization with the Photosensitizer Tin (II) Etiopurpurin Dichloride: A Pilot StudyJournal of Urology, VOL. 152, NO. 6 Part 1, (2129-2132), Online publication date: 1-Dec-1994.Bachor R, Shea C, Belmonte S and Hasan T (2018) Free and Conjugated Chlorin E6 in the Photodynamic Therapy of Human Bladder Carcinoma CellsJournal of Urology, VOL. 146, NO. 6, (1654-1658), Online publication date: 1-Dec-1991. Volume 143Issue 3March 1990Page: 630-633 Advertisement Copyright & Permissions© 1990 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Steven H. Selman More articles by this author Binsheng Qin More articles by this author Harold R. James More articles by this author Rick W. Keck More articles by this author Greta M. Garbo More articles by this author Alan R. Morgan More articles by this author Expand All Advertisement PDF downloadLoading ...