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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Aaptamine Alkaloids from the Vietnamese Sponge Aaptos sp

2009; SAGE Publishing; Volume: 4; Issue: 8 Linguagem: Inglês

10.1177/1934578x0900400813

ISSN

1934-578X

Autores

Larisa K. Shubina, Anatoly I. Kalinovsky, Sergey N. Fedorov, Oleg S. Radchenko, В. А. Денисенко, Pavel S. Dmitrenok, Sergey A. Dyshlovoy, Vladimir B. Krasokhin, Valentin A. Stonik,

Tópico(s)

Chemical Synthesis and Analysis

Resumo

A series of aaptamines, including one new alkaloid (1), were isolated from the marine sponge Aaptos sp. collected in Vietnamese waters. The structure of 1 was elucidated using NMR and HRESIMS, as well as by chemical transformation of 1 to the previously known aaptamine and established as 3-N-morpholinyl-9-demethyl(oxy)aaptamine. The isolated compounds showed a potential cancer preventive activity.

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