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Case Report. Colosplenic Fistula in a Patient Treated with Interleukin-2 for Malignant Melanoma

1997; Lippincott Williams & Wilkins; Volume: 21; Issue: 4 Linguagem: Inglês

10.1097/00004728-199707000-00031

1532-3145

Elizabeth S. Chun, Terrence C. Demos, Ellen R. Gaynor,

Biliary and Gastrointestinal Fistulas

Interleukin-2 (IL-2) therapy often causes gastrointestinal side effects and at least 8 cases of bowel perforation have been reported. The patient reported here developed a colosplenic fistula, diagnosed by CT, with no neoplastic involvement of these organs. Awareness of these complications of IL-2 can help lead to earlier diagnosis.