[Askin tumor. Rare neurogenic tumor with metastasis to mouth, jaw and face regions].
1989; National Institutes of Health; Volume: 13; Issue: 3 Linguagem: Inglês
Autores
Kathryn E. Meier, Hans‐Henning Horch, U. Fink, T Gain, W. Gössner,
Tópico(s)Cancer Diagnosis and Treatment
ResumoOne case of a malignant peripheral neuroectodermal tumor of the thoracopulmonary region (Askin-Tumor) is reported. The tumor represents a distinct pathologic entity of neuroectodermal origin. The patient developed a metastasis in the upper jaw and in a lumbar vertebra. Morphologic and immunocytochemical findings of this extremely rare tumor were described and differential diagnosis from other soft-tissue round-cell sarcomas, such as Ewing's sarcoma and neuroblastoma are discussed. Problems associated with the clinical behavior and treatment are outlined. The prognosis in most cases of Askin-tumor is poor. The recommended therapy is radical resection, irradiation and combination chemotherapy containing anthracyclines and a high dose of alkylating agents.
Referência(s)