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Polysomnography findings in spinocerebellar ataxia type 6

2016; Wiley; Volume: 25; Issue: 6 Linguagem: Inglês

10.1111/jsr.12439

1365-2869

Adriana Dourado Rueda, José Luiz Pedroso, Eveli Truksinas, Gilmar Fernandes do Prado, Fernando Morgadinho Santos Coelho, Orlando Graziani Póvoas Barsottini,

Sleep and Wakefulness Research

Summary Spinocerebellar ataxia type 6 ( SCA 6) is usually described as a pure ataxia syndrome. However, SCA 6 patients may have sleep complaints. In this paper, sleep disorders were investigated in patients with SCA 6. Twelve SCA 6 patients and 12 subjects matched by gender, age and body mass index (control group) underwent polysomnography and clinical investigation for sleep disorders. SCA 6 had a higher frequency of snoring ( P = 0.01), a higher index of awakening due to respiratory events ( P = 0.003) and central apnea events during sleep ( P = 0.024), a longer sleep Stage N1 ( P = 0.02) and a lower sleep Stage N3 ( P = 0.05) in SCA 6 patients than in control subjects. SCA 6 patients had a reduction in slow wave sleep and a higher frequency of snoring and respiratory disorders during sleep when compared to the control group.