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Importance and Timing of Prophylactic Antibiotics Inurology With A Special Reference to Growth and Kill Rates of E. Coli in Genitourinary Organs

1982; Lippincott Williams & Wilkins; Volume: 128; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)53076-1

1527-3792

Ole Steen Nielsen, Paul O. Madsen,

Urinary Bladder and Prostate Research

No AccessJournal of Urology1 Sep 1982Importance and Timing of Prophylactic Antibiotics Inurology With A Special Reference to Growth and Kill Rates of E. Coli in Genitourinary Organs Ole S. Nielsen, and Paul O. Madsen Ole S. NielsenOle S. Nielsen More articles by this author , and Paul O. MadsenPaul O. Madsen More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)53076-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We conducted an experimental study using rats to investigate the timing of prophylactic antibiotics in urological surgery and to evaluate the benefit from a single, prophylactic injection of an antibiotic. Another objective was to examine the growth and kill rates of Escherichia coli 06 in operated urinary tract organs. We were unable to demonstrate a short decisive period for the antibiotic treatment; it seems to vary with respect to the infecting organism and the infected organ. Administration of a single dose of antibiotic was sufficient to lower the rate of infection in the kidney and epididymis 24 hours after the operation and to eliminate bacteria completely from the prostate. The rate of growth and kill of E. coli 06 depended on the specific organs in which the infection took place. © 1982 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByGrabe M (2018) Antimicrobial Agents in Transurethral Prostatic ResectionJournal of Urology, VOL. 138, NO. 2, (245-252), Online publication date: 1-Aug-1987.Childs S, Wells W and Mirelman S (2018) Antibiotic Prophylaxis for Genitourinary Surgery in Community HospitalsJournal of Urology, VOL. 130, NO. 2, (305-308), Online publication date: 1-Aug-1983.Kunin C (2018) Editorial CommentJournal of Urology, VOL. 130, NO. 2, (308-308), Online publication date: 1-Aug-1983. Volume 128Issue 3September 1982Page: 608-614 Advertisement Copyright & Permissions© 1982 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Ole S. Nielsen More articles by this author Paul O. Madsen More articles by this author Expand All Advertisement Loading ...