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Gastroesophageal Reflux Laryngitis

2012; Springer Science+Business Media; Linguagem: Inglês

10.1002/9781444346220.ch29

1612-9067

Robert T. Kavitt, Michael F. Vaezi,

Helicobacter pylori-related gastroenterology studies

Gastroesophageal reflux disease is increasingly associated with ear, nose, and throat symptoms, including laryngitis. Many patients are unaware of the gastroesophageal etiology of their symptoms. A variety of criteria are used to diagnose this condition, including laryngoscopy, esophagogastroduodenoscopy, and the use of ambulatory pH and impedance monitoring. However, no test serves as the gold standard for the diagnosis given their lack of sensitivity and specificity for reflux disease. Numerous trials have assessed the role of proton pump inhibitor therapy in patients with laryngopharyngeal reflux and most have revealed no benefit to acid suppression over placebo. Gastroenterology and otolaryngology specialty societies have released various guidelines in recent years addressing diagnostic and therapeutic approaches to this prevalent and often difficult-to-treat condition. However, many uncertainties remain, including which patient subgroups might benefit from acid suppressive therapy. Future outcome studies are needed to assess the role of impedance–pH monitoring in this group of patients and to determine who might symptomatically benefit from medical or surgical intervention.