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Randomized Controlled Study of Chemoprophylaxis in Transurethral Prostatectomy

1993; Lippincott Williams & Wilkins; Volume: 150; Issue: 5 Part 2 Linguagem: Inglês

10.1016/s0022-5347(17)35876-7

1527-3792

Jouko Viitanen, Martti Talja, E. Jussila, M. Nurmi, J. Permi, Veli‐Matti Puolakka, Esa Rintala, Heli Salmela, J Tiitinen, Kari Tuhkanen, Jeffrey A. Elo,

Urinary Tract Infections Management

No AccessJournal of UrologyTransurethral Resection of the Prostate and Related Topics1 Nov 1993Randomized Controlled Study of Chemoprophylaxis in Transurethral Prostatectomy J. Viitanen, M. Talja, E. Jussila, M. Nurmi, J. Permi, V.-M. Puolakka, E. Rintala, H. Salmela, J. Tiitinen, K. Tuhkanen, and J. Elo J. ViitanenJ. Viitanen More articles by this author , M. TaljaM. Talja More articles by this author , E. JussilaE. Jussila More articles by this author , M. NurmiM. Nurmi More articles by this author , J. PermiJ. Permi More articles by this author , V.-M. PuolakkaV.-M. Puolakka More articles by this author , E. RintalaE. Rintala More articles by this author , H. SalmelaH. Salmela More articles by this author , J. TiitinenJ. Tiitinen More articles by this author , K. TuhkanenK. Tuhkanen More articles by this author , and J. EloJ. Elo More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)35876-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We studied 599 evaluable patients with benign prostatic hypertrophy at 7 urological units. Before transurethral prostatectomy the patients were randomized into 3 groups: group 1—197 patients given single-dose ceftriaxone (2 gm.), group 2—203 patients given 160/800mg. trimethoprim-sulfamethoxazole and group 3—199 controls given no antimicrobial prophylaxis. Patients with a preoperative indwelling catheter, positive urine culture, signs of active infection or preoperative antibiotic treatment were excluded. Postoperative infectious complications were demonstrated in 15 of 197 (7.6%), 25 of 203 (12.3%) and 43 of 199 (21.6%) patients in the study groups, respectively. The difference in infectious complications between groups 1 and 3 was statistically highly significant (p <0.01) and between groups 2 and 3 it was significant (p <0.05). Single-dose antibiotic prophylaxis proved to be useful in the prevention of serious infectious complications after transurethral prostatectomy. © 1993 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byQIANG W, JIANCHEN W, MacDONALD R, MONGA M and WILT T (2018) ANTIBIOTIC PROPHYLAXIS FOR TRANSURETHRAL PROSTATIC RESECTION IN MEN WITH PREOPERATIVE URINE CONTAINING LESS THAN 100,000 BACTERIA PER ML: A SYSTEMATIC REVIEWJournal of Urology, VOL. 173, NO. 4, (1175-1181), Online publication date: 1-Apr-2005.BERRY A and BARRATT A (2018) PROPHYLATIC ANTIBIOTIC USE IN TRANSURETHRAL PROSTATIC RESECTION: A META-ANALYSISJournal of Urology, VOL. 167, NO. 2 Part 1, (571-577), Online publication date: 1-Feb-2002.Gasser T, Wisard M and Frei R (2018) Oral Fleroxacin Prophylaxis in Transurethral SurgeryJournal of Urology, VOL. 156, NO. 1, (146-148), Online publication date: 1-Jul-1996. Volume 150Issue 5 Part 2November 1993Page: 1715-1717 Advertisement Copyright & Permissions© 1993 by The American Urological Association Education and Research, Inc.Keywordsprostateprostatic hypertrophyprostatectomyMetricsAuthor Information J. Viitanen More articles by this author M. Talja More articles by this author E. Jussila More articles by this author M. Nurmi More articles by this author J. Permi More articles by this author V.-M. Puolakka More articles by this author E. Rintala More articles by this author H. Salmela More articles by this author J. Tiitinen More articles by this author K. Tuhkanen More articles by this author J. Elo More articles by this author Expand All Advertisement PDF downloadLoading ...