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Zika Virus Infection Associated With Severe Thrombocytopenia

2016; Oxford University Press; Volume: 63; Issue: 9 Linguagem: Inglês

10.1093/cid/ciw476

1537-6591

Tyler M. Sharp, Jorge L. Muñoz‐Jordán, Janice Pérez‐Padilla, Melissa Bello-Pagán, Aidsa Rivera, Daniel M. Pastula, Jorge Salinas, Jose H. Martínez Mendez, Mónica Méndez, Ann M. Powers, Stephen H. Waterman, Brenda Rivera-García,

Vector-borne infectious diseases

Abstract We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.