Prevalence of Trichomoniasis, Bacterial Vaginosis and Candidiasis in Women Attending a Sexual Transmitted Infections and Gynaecologic Clinic using an Immunologic Latex Agglutination Test
2007; Volume: 6; Issue: 2 Linguagem: Inglês
10.5580/cd4
ISSN1528-8439
Tópico(s)Cervical Cancer and HPV Research
ResumoObjectives: Validation of a simple and rapid test for diagnosis of vaginitis diagnosis and to evaluate its performance in a population sample of women attending gynecologic and STIs clinic in the diagnosis of Candida albicans, Trichomonas vaginalis and Gardnerella vaginalis. Methods: Clinical sensitivity and specificity were determined for Gardnerella vaginalis with 459 vaginal secretions samples obtained from a Gynecological Clinic of Havana, using Gram staining as reference method. Prevalence study was carried out in a total of 113 non-pregnant women attending a gynecology and STIs clinic that were screened for STIs (VIH/AIDS, Gonorrhea, Hepatitis B, Syphilis, Condyloma, and Genital Herpes) and for vaginitis by of Trichomonas vaginalis, Gardnerella vaginalis and Candida albicans by an immunological method. Risk factors were surveyed among attended women. Prevalence, confidence intervals (with 5% error) and oOdds ratios were calculated. Results: In the case of Gardnerella vaginalis 24 (5.2%) of the clinical samples reacted with the negative control and were classified as inconclusive. Clinical sensitivity and specificity determined in the 435 remaining samples were 91% and 97% respectively. Diagnosed STIs were 3 women with Gonorrhea and 1 woman with Condyloma. Prevalence of trichomoniasis, bacterial vaginosis (gardnerellosis) and candidiasis were 43.36%, 31.86% and 13.27% respectively. From the declared risk factors and diagnosis was possible to observed a significant odds ratio >6 between trichomoniasis and promiscuous behavior confirming Trichomonas vaginalis STI condition. This was not the same for Gardnerella vaginalis where no relation was observed with STI risk factors., Ccandidiasis was not possible to correlate because of small number of cases diagnosed. The frequency of vaginitis symptoms and signs is shown in figure 2. Vaginal discharge was the most common symptom in women with any kind of vaginitis; the other more frequent symptoms or signs were colpitis, vulvar pruritus, abdominal pain, bleeding cervix and dyspareunia with no relation with the diagnosis. Conclusion: The kit validation showed results as other more sophisticated techniques as DNA hybridization test and its performance was as expected detecting Ttrichomoniasis wasas the most frequent cause of vaginitis in this sample and hadwith significant relation with promiscuous behavior confirming the STI condition of this infection. This study was financed by a grant from the Ministry of Public Health of the Republic of Cuba
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