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Synthesis of Fused Polycyclic Indoles by Brønsted Acid-Catalyzed Intramolecular Alkylation of Indoles with Alcohols

2015; American Chemical Society; Volume: 80; Issue: 20 Linguagem: Inglês

10.1021/acs.joc.5b02048

1520-6904

Anisley Suárez, Mukut Gohain, Manuel A. Fernández‐Rodríguez, Roberto Sanz,

Asymmetric Synthesis and Catalysis

An efficient methodology for the synthesis of a series of new fused polyclyclic indoles has been developed by Brønsted acid-catalyzed intramolecular Friedel-Crafts reactions of properly designed indolyl alcohols.