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Artigo Revisado por pares
BIBTEX RIS

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

2016; American Association for the Advancement of Science; Volume: 8; Issue: 344 Linguagem: Inglês

10.1126/scitranslmed.aad8278

ISSN

1946-6242

Autores

Johanna F. Dekkers, Gitte Berkers, Evelien Kruisselbrink, Annelotte M. Vonk, Hugo R. de Jonge, Hettie M. Janssens, Inez Bronsveld, E.A. van de Graaf, Edward E. S. Nieuwenhuis, Roderick H.J. Houwen, Frank P. Vleggaar, Johanna C. Escher, Yolanda B. de Rijke, Christof J. Majoor, Harry Heijerman, Karin M. de Winter–de Groot, Hans Clevers, Cornelis K. van der Ent, Jeffrey M. Beekman,

Tópico(s)

Asthma and respiratory diseases

Resumo

Rectal organoids from subjects with cystic fibrosis can be used to assess responses to drugs that modulate CFTR.

Referência(s)