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“Nephrogenic Adenoma”: An Unusual Metaplastic Change of Urothelium

1981; Lippincott Williams & Wilkins; Volume: 125; Issue: 2 Linguagem: Inglês

10.1016/s0022-5347(17)54990-3

1527-3792

Patricia O’Shea, Joseph F. Callaghan, John B. Lawlor, Vodur C. Reddy,

Bladder and Urothelial Cancer Treatments

No AccessJournal of Urology1 Feb 1981“Nephrogenic Adenoma”: An Unusual Metaplastic Change of Urothelium Patricia A. O’Shea, Joseph F. Callaghan, John B. Lawlor, and Vodur C. Reddy Patricia A. O’SheaPatricia A. O’Shea More articles by this author , Joseph F. CallaghanJoseph F. Callaghan More articles by this author , John B. LawlorJohn B. Lawlor More articles by this author , and Vodur C. ReddyVodur C. Reddy More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54990-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail “Nephrogenic adenoma” is a papillary bladder lesion of uncertain pathogenesis. We have studied 2 patients with this lesion for several years with serial biopsies in both cases. We believe that the natural history of “nephrogenic adenoma” and its invariable association with bladder irritation, coupled with the histopathologic and ultrastructural findings, strongly suggest that this “tumor” represents a papillary and glandular transformation of urothelium, in response to prolonged exposure to various injurious agents. It is best regarded as a metaplastic process rather than a hamartoma or a benign neoplasm. There is no reasonable basis for supposing that the process originates from mesonephric-derived epithelium. While not itself neoplastic nephrogenic metaplasia (our preferred term) is rarely associated with the late development of invasive but not, to date, metastasizing neoplasia. Routine cystoscopy would seem the most appropriate means of following these patients. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByNold S, Terry W, Cerniglia F, Hawkins E, Roth D and Gonzales E (2018) Nephrogenic Adenoma of the Bladder in ChildrenJournal of Urology, VOL. 142, NO. 6, (1545-1547), Online publication date: 1-Dec-1989.Gonzalez J, Watts J and Alderson T (2018) Nephrogenic Adenoma of the Bladder: Report of 10 CasesJournal of Urology, VOL. 139, NO. 1, (45-47), Online publication date: 1-Jan-1988.Schultz R, Bloch M, Tomaszewski J, Brooks J and Hanno P (2018) Mesonephric Adenocarcinoma of the BladderJournal of Urology, VOL. 132, NO. 2, (263-265), Online publication date: 1-Aug-1984.Satodate R, Koike H, Sasou S, Ohori T and Nagane Y (2018) Nephrogenic Adenoma of the UreterJournal of Urology, VOL. 131, NO. 2, (332-334), Online publication date: 1-Feb-1984.Ritchey M, Novicki D and Schultenover S (2018) Nephrogenic Adenoma of Bladder: A Report of 8 CasesJournal of Urology, VOL. 131, NO. 3, (537-539), Online publication date: 1-Mar-1984.Navarre R, Loening S, Platz C, Narayana A and Culp D (2018) Nephrogenic Adenoma: A Report of 9 Cases and Review of the LiteratureJournal of Urology, VOL. 127, NO. 4, (775-779), Online publication date: 1-Apr-1982. Volume 125Issue 2February 1981Page: 249-252 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Patricia A. O’Shea More articles by this author Joseph F. Callaghan More articles by this author John B. Lawlor More articles by this author Vodur C. Reddy More articles by this author Expand All Advertisement Loading ...