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The Age-related Eye Disease Study (Areds)

2002; Oxford University Press; Volume: 60; Issue: 9 Linguagem: Inglês

10.1301/002966402320387215

1753-4887

Billy R. Hammond, Mary Ann Johnson,

Connexins and lens biology

Some of the earliest and best known manifestations of malnutrition involve visual disorders, such as blindness that results from vitamin A deficiency. Interest is now being focused on the role of nutrition in the prevention and treatment of chronic age-related disorders. The Age-related Eye Disease Study (AREDS) was conducted in order to determine whether high-dose supplementation could influence the natural progres sion of eye disease in older Americans. AREDS found that prospective administration of purified vitamin C, vitamin E, beta-carotene, zinc, and copper had some benefits for age-related maculopathy, but had virtually no impact on the progression of cataracts.