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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Time-dependent changes in mortality and transformation risk in MDS

2016; Elsevier BV; Volume: 128; Issue: 7 Linguagem: Inglês

10.1182/blood-2016-02-700054

ISSN

1528-0020

Autores

Michael Pfeilstöcker, Heinz Tuechler, Guillermo Sanz, Julie Schanz, Guillermo Garcia‐Manero, Françesc Solé, John M. Bennett, David Bowen, Pierre Fenaux, François Dreyfus, Hagop M. Kantarjian, Andrea Kuendgen, Luca Malcovati, Mario Cazzola, Jaroslav Čermák, Christa Fonatsch, Michelle M. Le Beau, Marilyn L. Slovak, Alessandro Levis, Michael Luebbert, Jaroslaw P. Maciejewski, Sigrid Machherndl‐Spandl, Silvia M. M. Magalhães, Yasushi Miyazaki, Mikkael A. Sekeres, Wolfgang R. Sperr, Reinhard Stauder, Sudhir Tauro, Peter Valent, Teresa Vallespı́, Arjan A. van de Loosdrecht, Ulrich Germing, Detlef Haase, Peter L. Greenberg,

Tópico(s)

Chronic Myeloid Leukemia Treatments

Resumo

Key Points Hazards regarding mortality and leukemic transformation in MDS diminish over time in higher-risk but remain stable in lower-risk patients. This change of hazard indicates time-dependent attenuation of power of basal risk scores, which is relevant for clinical decision making.

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