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Erectile Dysfunction in Diabetic Men: The Neurological Factor Revisited

1994; Lippincott Williams & Wilkins; Volume: 151; Issue: 4 Linguagem: Inglês

10.1016/s0022-5347(17)35113-3

1527-3792

Bart L.H. Bemelmans, E.J.H. Meuleman, Wim H. Doesburg, S. L. H. Notermans, F.M.J. Debruyne,

Hormonal and reproductive studies

No AccessJournal of Urology1 Apr 1994Erectile Dysfunction in Diabetic Men: The Neurological Factor Revisited Bart L.H. Bemelmans, Eric J.H. Meuleman, Wim H. Doesburg, Servaas L.H. Notermans, and Frans M.J. Debruyne Bart L.H. BemelmansBart L.H. Bemelmans , Eric J.H. MeulemanEric J.H. Meuleman , Wim H. DoesburgWim H. Doesburg , Servaas L.H. NotermansServaas L.H. Notermans , and Frans M.J. DebruyneFrans M.J. Debruyne View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)35113-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail In the literature the importance of the neurological factor in the etiology of erectile dysfunction in patients with diabetes mellitus is subject to debate. We report on the findings of neurophysiological investigations in 27 impotent and 30 potent diabetic patients, as well as 102 impotent nondiabetic patients. Additionally, hormonal and vascular evaluations were done. The neurophysiological evaluations consisted of assessment of somatic as well as autonomic sensory nerves, by measuring the latencies of somatosensory evoked potentials of the posterior tibial and pudendal nerves, and of the bulbocavernosus and urethro-anal reflexes. The results show a higher incidence of more severe peripheral and autonomic sensory neuropathy in impotent diabetic men. Also, a preponderance of abnormal intracavernous pharmacological tests, suggesting vasculogenic impotence, was found in impotent diabetic patients. No important endocrinological differences were found among the 3 groups under investigation. Significant differences occurred for plasma glucose and glycosylated hemoglobin. We conclude that diabetic urogenital sensory neuropathy has a crucial role in the etiology of diabetic impotence. Angiopathy seems to be of secondary importance. The results show that poor diabetes regulation is associated with diabetic impotence. © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byBENNETT N, KIM J, WOLFE D, SASAKI K, YOSHIMURA N, GOINS W, HUANG S, NELSON J, de GROAT W, GLORIOSO J and CHANCELLOR M (2018) IMPROVEMENT IN ERECTILE DYSFUNCTION AFTER NEUROTROPHIC FACTOR GENE THERAPY IN DIABETIC RATSJournal of Urology, VOL. 173, NO. 5, (1820-1824), Online publication date: 1-May-2005.COSTABILE R (2018) Optimizing Treatment for Diabetes Mellitus Induced Erectile DysfunctionJournal of Urology, VOL. 170, NO. 2S, (S35-S39), Online publication date: 1-Aug-2003.LEFAUCHEUR J, YIOU R, SALOMON L, CHOPIN D and ABBOU C (2018) ASSESSMENT OF PENILE SMALL NERVE FIBER DAMAGE AFTER TRANSURETHRAL RESECTION OF THE PROSTATE BY MEASUREMENT OF PENILE THERMAL SENSATIONJournal of Urology, VOL. 164, NO. 4, (1416-1419), Online publication date: 1-Oct-2000.ROMEO J, SEFTEL A, MADHUN Z and ARON D (2018) SEXUAL FUNCTION IN MEN WITH DIABETES TYPE 2: ASSOCIATION WITH GLYCEMIC CONTROLJournal of Urology, VOL. 163, NO. 3, (788-791), Online publication date: 1-Mar-2000.Bemelmans B, Hendrikx L, Koldewijn E, Lemmens W, Debruyne F and Meuleman E (2018) Comparison of Biothesiometry and Neurourophysiological Investigations for the Clinical Evaluation of Patients with Erectile DysfunctionJournal of Urology, VOL. 153, NO. 5, (1483-1486), Online publication date: 1-May-1995. Volume 151Issue 4April 1994Page: 884-889 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.Keywordsneurophysiologypenile erectionimpotencediabetesMetricsAuthor Information Bart L.H. Bemelmans More articles by this author Eric J.H. Meuleman More articles by this author Wim H. Doesburg More articles by this author Servaas L.H. Notermans More articles by this author Frans M.J. Debruyne More articles by this author Expand All Advertisement PDF downloadLoading ...