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The COPD Assessment Test

2016; Elsevier BV; Volume: 150; Issue: 5 Linguagem: Inglês

10.1016/j.chest.2016.06.016

1931-3543

Nisha Gupta, Lancelot Pinto, Andrea Benedetti, Pei Zhi Li, Wan C. Tan, Shawn D. Aaron, Kenneth R. Chapman, J. Mark FitzGerald, Paul Hernandez, Darcy Marciniuk, François Maltais, Denis E. O’Donnell, Don D. Sin, Brandie Walker, Jean Bourbeau, Jean Bourbeau, Wan C. Tan, J. Mark FitzGerald, Don D. Sin, Darcy Marciniuk, Denis E. O’Donnell, Paul Hernandez, Kenneth R. Chapman, Robert Cowie, Shawn D. Aaron, François Maltais, Jonathon Samet, Milo A. Puhan, Qutayba Hamid, James C. Hogg, Jean Bourbeau, Carole Baglole, Carole Jabet, Palmina Mancino, Yvan Fortier, Wan C. Tan, Don D. Sin, Sheena Tam, Jeremy Road, Joe Comeau, Adrian Png, Harvey O. Coxson, Miranda Kirby, Jonathon Leipsic, Cameron Hague, Mohsen Sadatsafavi, Teresa To, Andrea S. Gershon, Wan C. Tan, Harvey O. Coxson, Jean Bourbeau, Peizhi Li, Jean-Francois Duquette, Yvan Fortier, Andrea Benedetti, Denis Jensen, Denis E. O’Donnell, Wan C. Tan, Christine Lo, Sarah Cheng, Cindy Fung, Nancy Haynes, Junior Chuang, Liyun Zheng, Jean Bourbeau, Palmina Mancino, David Latreille, Jacinthe Baril, Laura Labonté, Kenneth R. Chapman, Patricia McClean, Nadeen Audisho, Robert Cowie, Ann Cowie, Curtis Dumonceaux, Lisette Machado, Paul Hernandez, Scott Fulton, Kristen Osterling, Shawn D. Aaron, Kathy Vandemheen, Gay Pratt, Amanda Bergeron, Denis E. O’Donnell, Matthew McNeil, Kate Whelan, François Maltais, Cynthia Brouillard, Darcy Marciniuk, Ron Clemens, Janet Baran,

Respiratory Support and Mechanisms

The COPD Assessment Test (CAT) is a valid disease-specific questionnaire measuring health status. However, knowledge concerning its use regarding patient and disease characteristics remains limited. Our main objective was to assess the degree to which the CAT score varies and can discriminate between specific patient population groups.The Canadian Cohort Obstructive Lung Disease (CanCOLD) is a random-sampled, population-based, multicenter, prospective cohort that includes subjects with COPD (Global Initiative for Chronic Obstructive Lung Disease [GOLD] classifications 1 to 3). The CAT questionnaire was administered at three visits (baseline, 1.5 years, and 3 years). The CAT total score was determined for sex, age groups, smoking status, GOLD classification, exacerbations, and comorbidities.A total of 716 subjects with COPD were included in the analysis. The majority of subjects (72.5%) were not previously diagnosed with COPD. The mean FEV1/FVC ratio was 61.1 ± 8.1%, with a mean FEV1 % predicted of 82.3 ± 19.3%. The mean CAT scores were 5.8 ± 5.0, 9.6 ± 6.7, and 16.1 ± 10.0 for GOLD 1, 2, and 3+ classifications, respectively. Higher CAT scores were observed in women, current smokers, ever-smokers, and subjects with a previous diagnosis of COPD. The CAT was also able to distinguish between subjects who experience exacerbations vs those who had no exacerbation.These results suggest that the CAT, originally designed for use in clinically symptomatic patients with COPD, can also be used in individuals with mild airflow obstruction and newly diagnosed COPD. In addition, the CAT was able to discriminate between sexes and subjects who experience frequent and infrequent exacerbations.ClinicalTrials.gov; No.: NCT00920348; Study ID No.: IRO-93326.