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Characteristics, outcome, and response to therapy of multirefractory chronic immune thrombocytopenia

2016; Elsevier BV; Volume: 128; Issue: 12 Linguagem: Inglês

10.1182/blood-2016-03-704734

1528-0020

Matthieu Mahévas, Mathieu Gerfaud‐Valentin, Guillaume Moulis, Louis Terriou, S. Audia, Sophie Guénin, G. Le Guenno, Gilles Salles, O. Lambotte, Nicolas Limal, Jean‐François Viallard, Stéphane Chèze, Cécile Tomowiak, Bruno Royer, A. Néel, O. Debouverie, A. Hot, I. Durieu, Antoinette Perlat, Manuel Cliquennois, Clémence Deteix, Marc Michel, Bertrand Godeau,

Autoimmune Bullous Skin Diseases

Key Points The baseline characteristics of multirefractory ITP differed from “typical” ITP, outcome was severe, and was associated with high morbidity and mortality. Combining immunosuppressant therapy with a thrombopoietin-receptor agonist may be a relevant option for these patients.