Epidemiology of myasthenia gravis in Northern Portugal: Frequency estimates and clinical epidemiological distribution of cases
2016; Wiley; Volume: 54; Issue: 3 Linguagem: Inglês
10.1002/mus.25068
ISSN1097-4598
AutoresErnestina Santos, Estér Coutinho, Isabel Moreira, Ana Martins da Silva, Dina Lopes, Henrique Costa, Fernando Silveira, Goreti Nadais, Hugo Morais, João Martins, Maria Ceu Branco, Andreia Veiga, Rosa Santos Silva, Augusto Ferreira Umpiérrez, Filipa Sousa, Marta Freijo, Ilda Matos, Rui André, Luís Negrão, Carla Fraga, Manuela Santos, Mafalda Sampaio, Carlos Lopes, Maria Isabel Leite, Guilherme Gonçalves,
Tópico(s)Peripheral Neuropathies and Disorders
ResumoIn this study we estimated the prevalence, incidence, and mortality of myasthenia gravis (MG) in northern Portugal and characterized the clinical features of the patients identified.We used 2 data sources: clinical records from the hospitals and pyridostigmine prescription registers.On December 31, 2013, we estimated a point prevalence of 111.7 patients per million population. The highest prevalence was observed in the group >65 years of age, especially in men (288.1 per million). During 2013, we estimated an incidence rate of 6.3 per million per year. Among women, the incidence rate was highest in the 15-49-year age group; in men, incidence increased with age up to 22.1 per million in those >65 years old. The MG-related mortality rate was 0.5 per million.These figures are in keeping with similar studies and emphasize the importance of diagnosis and management of MG in elderly populations. Muscle Nerve 54: 413-421, 2016.
Referência(s)