Produção Nacional
Revisado por pares
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
2016; BioMed Central; Volume: 11; Issue: 1 Linguagem: Inglês
10.1186/s13017-016-0089-y
ISSN1749-7922
AutoresMassimo Sartelli, Dieter Weber, Étienne Ruppé, Matteo Bassetti, Brian J. Wright, Luca Ansaloni, Fausto Catena, Federico Coccolini, Fikri M. Abu‐Zidan, Raúl Coimbra, Ernest E. Moore, Frederick A. Moore, Ronald V. Maier, Jan J. De Waele, Andrew W. Kirkpatrick, Ewen A. Griffiths, Christian Eckmann, Adrian Brink, John E. Mazuski, Addison K. May, Robert G. Sawyer, Dominik Mertz, Philippe Montravers, Anand Kumar, Jason A. Roberts, Jean‐Louis Vincent, Richard Watkins, Warren Lowman, Brad Spellberg, Iain J. Abbott, A. R. K. Adesunkanmi, Sara Al-Dahir, Majdi N. Al‐Hasan, Ferdinando Agresta, Asma Al-Thani, Shamshul Ansari, Rashid Ansumana, Goran Augustin, Miklosh Bala, Zsolt J. Balogh, Oussama Baraket, Aneel Bhangu, Marcelo A. Beltrán, Michaël Bernhard, Walter L. Biffl, Marja A. Boermeester, Stephen M. Brecher, Jill R. Cherry‐Bukowiec, Otmar R. Buyne, Miguel Caínzos, Kelly A. Cairns, Adrián Camacho-Ortíz, Sujith J Chandy, Asri Che Jusoh, Alain Chichom‐Mefire, Caroline Colijn, Francesco Corcione, Yunfeng Cui, Daniel Curcio, Samir Delibegović, Zaza Demetrashvili, Belinda De Simone, Sameer Dhingra, José J. Diaz, Isidoro Di Carlo, Angel Dillip, Salomone Di Saverio, Michael P. Doyle, Gereltuya Dorj, Agron Dogjani, Hervé Dupont, Soumitra R. Eachempati, Mushira Enani, Egiev Vn, Mutasim M. Elmangory, Paula Ferrada, Joseph R A Fitchett, Gustavo Pereira Fraga, Nathalie Guessennd, Helen Giamarellou, Wagih Ghnnam, George Gkiokas, Staphanie R. Goldberg, Carlos Augusto Gomes, Harumi Gomi, Manuel Guzmán-Blanco, Mainul Haque, Sonja Hansen, Andreas Hecker, W. R. Heizmann, Torsten Herzog, Adrien Montcho Hodonou, Suk‐Kyung Hong, Reinhold Kafka‐Ritsch, Lewis J. Kaplan, Garima Kapoor, Aleksandar Karamarković, Martin G. Kees, Jakub Kenig, Ronald Kiguba, Peter K. Kim, Yoram Kluger, Vladimir Khokha, Kaoru Koike, Kenneth Yuh Yen Kok, Victor Kong, Matthew C. Knox, Kenji Inaba, Arda Işık, Katia Iskandar, Rao R. Ivatury, Maurizio Labbate, Francesco M. Labricciosa, Pierre-François Laterre, Rifat Latifi, Jae Gil Lee, Young R. Lee, Marc Léone, Ari Leppäniemi, Yousheng Li, Stephen Y. Liang, Tonny Loho, Marc Maegele, Sydney Malama, Hany E. Marei, Ignacio Martín‐Loeches, Sanjay Marwah, Amos Massele, Michael McFarlane, Renato Bessa Melo, Ionuț Negoi, David P. Nicolau, Carl Erik Nord, Richard Ofori‐Asenso, AbdelKarim H. Omari, Carlos A. Ordóñez, Mouaqit Ouadii, Gerson Alves Pereira Júnior, Diego Piazza, G. Pupelis, Timothy M. Rawson, Miran Rems, Sandro Rizoli, Claudio Rocha, Boris Sakakhushev, Miguel Sánchez García, Norio Sato, Helmut Alfredo Segovia Lohse, Gabriele Sganga, Boonying Siribumrungwong, Vishal G. Shelat, Kjetil Søreide, Rodolfo Soto, Peep Talving, Jonathan Tilsed, Jean‐François Timsit, Gabriel Trueba, Ngo Tat Trung, Jan Ulrych, Harry van Goor, András Vereczkei, Ravinder Vohra, Imtiaz Wani, Waldemar Uhl, Yonghong Xiao, Kuo-Ching Yuan, Sanoop Koshy Zachariah, J.-R. Zahar, Tanya L. Zakrison, Antonio Corcione, Rita Maria Melotti, Claudio Viscoli, P. Viale,
Tópico(s)Appendicitis Diagnosis and Management
ResumoIntra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
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