Radio-Chemotherapy of Anal Cancer
1998; SAGE Publishing; Volume: 84; Issue: 2 Linguagem: Inglês
10.1177/030089169808400224
ISSN2038-2529
AutoresR Zucali, Roberto Doci, Rado Kenda, Laura Lozza, S. Tana, Francesca Valvo,
Tópico(s)Metastasis and carcinoma case studies
ResumoConventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotherapy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80% of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.
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