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Characteristics of β-endorphin-induced behavioral activation and immobilization

1979; Palgrave Macmillan; Linguagem: Inglês

10.1007/978-1-349-04015-5_28

David S. Segal, Ronald G. Browne, Amy T. Arnsten, David C. Derrington, Floyd E. Bloom, Arthur V. Davis, Roger Guillemin, Nicholas Ling,

Receptor Mechanisms and Signaling

β-endorphin produces a broad spectrum of dose-and time-related behavioral effects, ranging from hyperactivity to rigid immobility (Bloom et al., 1976; Segal et al., 1977). Our efforts to characterize further these effects and to compare them with the behavioral actions of opiates are described below.