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Síntese de N -glicosilsulfonamidas derivadas de d-glicose e N -acetilglicosamina

2015; Brazilian Chemical Society; Volume: 38; Issue: 8 Linguagem: Inglês

1678-7064

Lucas Lopardi Franco, Mário C. Brandão, José Dias de Souza Filho, Ricardo José Alves,

Enzyme Catalysis and Immobilization

Herein, we report the synthesis of β-N-glycosylsulfonamides derivatives of D-glucose and N-acetylglucosamine using conventional methods. We also describe a procedure that allows the preparation of these compounds in good yields without the anomerization of the intermediate glycosylamines. This method includes the intermediates obtained from the less reactive 1- and 2-naphthalenesulfonyl chlorides.