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Radiation Therapy for Soft Tissue Sarcoma

2016; Elsevier BV; Volume: 25; Issue: 4 Linguagem: Inglês

10.1016/j.soc.2016.05.012

1558-5042

Nicole Larrier, Brian G. Czito, David G. Kirsch,

Cardiac tumors and thrombi

Soft tissue sarcomas are rare mesenchymal cancers that pose a treatment challenge. Although small superficial soft tissue sarcomas can be managed by surgery alone, adjuvant radiotherapy in addition to limb-sparing surgery substantially increases local control of extremity sarcomas. Compared with postoperative radiotherapy, preoperative radiotherapy doubles the risk of a wound complication, but decreases the risk for late effects, which are generally irreversible. For retroperitoneal sarcomas, intraoperative radiotherapy can be used to safely escalate the radiation dose to the tumor bed. Patients with newly diagnosed sarcoma should be evaluated before surgery by a multidisciplinary team that includes a radiation oncologist.