
Amphotericin B lipid complex in the treatment of severe paracoccidioidomycosis: a case series
2016; Elsevier BV; Volume: 48; Issue: 4 Linguagem: Inglês
10.1016/j.ijantimicag.2016.06.011
ISSN1872-7913
AutoresPaulo Mendes Peçanha, Stella de Souza, Aloísio Falqueto, Tânia Regina Grão-Veloso, Ludmila Ventura Lírio, Carlos Urbano Gonçalves Ferreira, Aline Rocha Santos, Hélbia Garcia Costa, Lúcia Renata Meirelles de Souza, Felipe Francisco Tuon,
Tópico(s)Nail Diseases and Treatments
ResumoAmphotericin B deoxycholate is the main option for intravenous (i.v.) treatment of severe paracoccidioidomycosis (PCM). This is the first report of amphotericin B lipid complex (ABLC) in the treatment of PCM. Among 28 patients, cure was achieved in all patients (100%) using ABLC. Mean and median daily doses of ABLC were 3.39 mg/kg/day and 3.35 mg/kg/day, respectively. ABLC may be a choice in the treatment of severe forms of PCM or when i.v. options are required.
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