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Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans – joint RENEB and EURADOS inter-laboratory comparisons

2016; Taylor & Francis; Volume: 93; Issue: 1 Linguagem: Inglês

10.1080/09553002.2016.1206233

1362-3095

Elizabeth Ainsbury, Christophe Badie, Stephen Barnard, Grainne Manning, Jayne Moquet, Michael Abend, Ana Antunes, Leonardo Barrios, C. Bassinet, Christina Beinke, Emanuela Bortolin, Lily Bossin, Clare Bricknell, Kamil Brzóska, Iwona Buraczewska, Carlos Huertas-Castaño, Zina Čemusová, Maria Christiansson, Santiago Mateos, Guillaume Cosler, Sara Della Monaca, F Desangles, Michael Discher, Inmaculada Domı́nguez, Sven Doucha-Senf, J. D. Eakins, P. Fattibene, Silvia Filippi, Monika Frenzel, Dimka Georgieva, Eric Grégoire, Kamilė Guogytė, Valeria Hadjidekova, Ljubomira Popova, Rositsa Hristova, Maria Karakosta, Enikő Kis, Ralf Kriehuber, Jungil Lee, David Lloyd, Katalin Lumniczky, Fiona M. Lyng, Ellina Macaeva, Matthaeus Majewski, S. Vanda Martins, Stephen McKeever, Aidan D. Meade, Dinesh Medipally, Roberta Meschini, Radhia M’kacher, Octávia Monteiro Gil, Alegria Montero, M. Echevarría Moreno, Mihaela Noditi, Ursula Oestreicher, Dominik Oskamp, F. Palitti, Vincenzo Palma, Gabriel E. Pantelias, J. Pâteux, Clarice Patrono, Gaetano Pepe, Matthias Port, María Jesús Prieto, Maria Cristina Quattrini, Roel Quintens, Michelle Ricoul, Laurence Roy, Laure Sabatier, Natividad Sebastià, Sergey Sholom, Sylwester Sommer, Albena Staynova, Sonja Strunz, Georgia I. Terzoudi, Antonella Testa, F. Trompier, Marco Valente, Olivier Van Hoey, I. Veronese, Andrzej Wójcik, Clemens Woda,

Plant Genetic and Mutation Studies

Purpose: RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation.Materials and methods: The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones.Results: In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential for each of the candidate techniques.Conclusions: Further work is required before the new methods can be included within the suite of reliable dosimetry methods for use by RENEB partners and others in routine and emergency response scenarios.