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Comparative analysis of brilliant blue G and an intracameral illuminator in assisting visualization of the anterior capsule in eyes with vitreous hemorrhage

2016; Lippincott Williams & Wilkins; Volume: 42; Issue: 7 Linguagem: Inglês

10.1016/j.jcrs.2016.03.038

1873-4502

Young Min Park, Jung Yul Park, Jong Soo Lee, Ji Eun Lee, Ik Soo Byon, Sung Who Park,

Glaucoma and retinal disorders

To compare the safety and efficacy of 0.025 mg/mL brilliant blue G (BBG) and an intracameral illuminator for visualizing the anterior capsule.University-based tertiary referral center, South Korea.Retrospective cases series.The medical records of patients with vitreous hemorrhage for which they had pars plana vitrectomy and cataract surgery were retrospectively reviewed. The patients were classified into 2 groups. The BBG group comprised patients having capsule staining with BBG. The illuminator group comprised patients who had capsulorhexis assisted with an intracameral illuminator. The status of the endothelial cells was analyzed.There were 27 eyes in the BBG group and 35 eyes in the illuminator group. In the BBG group, endothelial cell density (ECD) was reduced 3 months after surgery (10.6% loss) (P = .003). The illuminator group had no significant loss (1.5% loss) (P = .264). The ECD loss was greater in the BBG group than the illuminator group 3 months after surgery (P = .01). There was no statistically significant difference in the coefficient of variation of cell area or percentage of hexagonal cells between the 2 groups.The ECD loss was higher in eyes with 0.025 mg/mL BBG staining than in eyes using an intracameral illuminator. Further studies are necessary to establish the safety profile of BBG on the endothelium.None of the authors has a financial or proprietary interest in any material or method mentioned.