Is There a Need for Viral Load Testing to Assess Treatment Failure in HIV-Infected Patients Who Are about to Change to Tenofovir-Based First-Line Antiretroviral Therapy? Programmatic Findings from Myanmar

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Is There a Need for Viral Load Testing to Assess Treatment Failure in HIV-Infected Patients Who Are about to Change to Tenofovir-Based First-Line Antiretroviral Therapy? Programmatic Findings from Myanmar

2016; Public Library of Science; Volume: 11; Issue: 8 Linguagem: Inglês

10.1371/journal.pone.0160616

ISSN

1932-6203

Autores

Nay Thiha, Palanivel Chinnakali, Anthony Harries, Myint Shwe, Thanumalaya Perumal Balathandan, Sai Thein Than Tun, Mrinalini Das, Htay Htay Tin, Yi Yi, F. Babin, Thi Thi Lwin, Philippe Clevenbergh,

Tópico(s)

HIV Research and Treatment

Resumo

WHO recommends that stavudine is phased out of antiretroviral therapy (ART) programmes and replaced with tenofovir (TDF) for first-line treatment. In this context, the Integrated HIV Care Program, Myanmar, evaluated patients for ART failure using HIV RNA viral load (VL) before making the change. We aimed to determine prevalence and determinants of ART failure in those on first-line treatment.

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Is There a Need for Viral Load Testing to Assess Treatment Failure in HIV-Infected Patients Who Are about to Change to Tenofovir-Based First-Line Antiretroviral Therapy? Programmatic Findings from Myanmar