Portal de Periódicos da CAPES

Adherence to Childhood Tuberculosis Treatment in Mozambique

2016; Oxford University Press; Linguagem: Inglês

10.1093/tropej/fmw048

1465-3664

Elisa López‐Varela, Guillermo Sequera, Alberto L. García‐Basteiro, Orvalho Augusto, Khátia Munguambe, Jahit Sacarlal, Pedro L. Alonso,

Adolescent and Pediatric Healthcare

There is limited literature regarding adherence rates for the treatment of tuberculosis (TB) in children. We aimed to describe TB treatment outcomes and adherence as well as to evaluate associated factors to poor adherence in Mozambican children.This is a sub-study of a community TB incidence study among children 3 weeks to treatment completion.Fifty TB treatments were assessed. Forty-four (88.0%) patients completed treatment, two (4.0%) died during treatment and four (8.0%) were lost to follow-up. Incomplete adherence was observed in 31.3% (15 of 48) of cases and was associated with malnutrition or history of a migrant mother.Although treatment outcome is overall good, there is still a significant proportion of incomplete adherence. Further larger paediatric TB cohorts and qualitative approaches are needed to assess and confirm potential factors for non-adherence.