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Extracorporeal blood purification for sepsis

2016; Hong Kong Academy of Medicine; Linguagem: Inglês

10.12809/hkmj164876

2226-8707

Hoi‐Ping Shum, WW Yan, Tak Mao Chan,

Mechanical Circulatory Support Devices

It has been speculated that extracorporeal blood purification therapies might improve the clinical outcome for patients with severe sepsis, with or without acute kidney injury, since the removal of inflammatory mediators and/or bacterial toxins from circulation could modulate the inflammatory responses that result in organ damage.Despite initial enthusiasm based on promising preliminary results, subsequent investigations did not show sustainable survival benefit.We review the principles and development of blood purification techniques for sepsis and septic acute kidney injury. Extracorporeal blood purification for sepsis