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Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980–2013): an analysis of population-based data in relation to socio-economic changes

2016; Dove Medical Press; Volume: Volume 9; Linguagem: Inglês

10.2147/ott.s112187

1178-6930

Aleksandra Czerw, Tomasz Banaś, Grzegorz Juszczyk, Kazimierz Pityński, Dorota Niewegłowska, Artur Ludwin,

Multiple and Secondary Primary Cancers

Objectives: This study aimed to analyze incidence and mortality trends in breast cancer (BC), corpus uteri cancer (CUC), and ovarian cancer (OC) in Poland in the context of sociodemographic changes. Materials and methods: Incidence and mortality data (1980–2013) were retrieved from the Polish National Cancer Registry, while socioeconomic data (1960–2013) were obtained from the World Bank. Age-standardized incidence and mortality rates were calculated by direct standardization, and join-point regression was performed to describe trends using the average annual percentage change (AAPC). Results: A significant decrease in birth and fertility rates and a large increase in gross domestic product were observed together with a decrease in the total mortality rate among women, as well as an increase in life expectancy for women. A large, significant increase in BC incidence was observed (AAPC 1980–1990 2.14, AAPC 1990–1996 4.71, AAPC 1996–2013 2.21), with a small but significant decrease in mortality after a slight increase (AAPC 1980–1994 0.52, AAPC 1994–2013 −0.66). During the period 1980–2013, a significant increase in CUC incidence (AAPC 1980–1994 3.7, AAPC 1994–2013 1.93) was observed, with an initial mortality-rate reduction followed by a significant increase (AAPC 1980–2006 −1.12, AAPC 2006–2013 3.74). After the initial increase of both OC incidence and mortality from 1994, the incidence rate decreased significantly (AAPC 1980–1994 2.98, AAPC 1994–2013 −0.49), as did the mortality rate (AAPC 1980–1994 0.52, AAPC 1994–2013 −0.66). Conclusion: After 1994, a decrease in OC incidence was found, while the incidence of BC and CUC continued to increase. A reduction in mortality rate was observed for BC and OC predominantly at the end of the study period, while for CUC, after a long decreasing mortality trend, a significant increase was observed. Keywords: average annual percentage change, breast cancer, corpus uteri cancer, epidemiology, incidence, mortality, ovarian cancer