Portal de Periódicos da CAPES

Plant expression systems, a budding way to confront chikungunya and Zika in developing countries?

2016; Faculty of 1000; Volume: 5; Linguagem: Inglês

10.12688/f1000research.9502.1

2046-1402

Jaime A. Cardona‐Ospina, Juan Carlos Arias, Lida Inés Mancilla, Luis Gonzaga Gutiérrez-López,

CRISPR and Genetic Engineering

Plant expression systems could be used as biofactories of heterologous proteins that have the potential to be used with biopharmaceutical aims and vaccine design. This technology is scalable, safe and cost-effective and it has been previously proposed as an option for vaccine and protein pharmaceutical development in developing countries. Here we present a proposal of how plant expression systems could be used to address Zika and chikungunya outbreaks through development of vaccines and rapid diagnostic kits.