Artigo Acesso aberto Produção Nacional Revisado por pares

Congenital Chikungunya Virus Infection after an Outbreak in Salvador, Bahia, Brazil

2016; Thieme Medical Publishers (Germany); Volume: 06; Issue: 03 Linguagem: Inglês

10.1055/s-0036-1587323

ISSN

2157-6998

Autores

Gúbio Soares Campos, Igor D. Bandeira, Silvia Sardi, Lilian T. Costa, Flávia Santos, Carlos Ribeiro, Alena Jardim, Ana Cecília Travassos Santiago, Patrícia de Oliveira, Lícia Moreira, Priscila Pinheiro Ribeiro Lyra,

Tópico(s)

Global Maternal and Child Health

Resumo

There is little information about the congenital chikungunya virus (CHIKV) transmission. We describe two cases of well-documented congenital CHIKV infection in Salvador-Brazil, where CHIKV has been identified since 2014. The outbreak in the city led to the clinical CHIKV diagnoses of both pregnant women 2 days before delivery. Urine and blood samples from the mothers and newborns were collected and tested for reverse transcription-polymerase chain reaction (PCR) analysis for Zika, dengue, and CHIKV. Both neonates and mothers had positive urine and serum PCR results for CHIKV. The newborns had significant perinatal complications and were admitted to the neonatal intensive care unit. The purpose of our case report is to show how severe congenital CHIKV infection can be and the importance to include CHIKV infection in the differential diagnosis of neonatal sepsis when mothers have clinical signs of the disease and live in an affected area.

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