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Study of Shuchi-Bushi, a Powder Type of Aconiti Tuber after being Autoclaved, Especially Concerning Side Effects-Usage and Dosage of Shuchi-Bushi from This Study-

2005; Japan Society for Oriental Medicine; Volume: 56; Issue: 5 Linguagem: Inglês

10.3937/kampomed.56.797

1882-756X

Kazuhiko NAGASAKA, T. Tatsumi, Michio NATORI, Hiroaki HIKIAMI,

Bioactive Natural Diterpenoids Research

Aconitum carmichaeli debeaux is an essential herbal medicine that possess anti-inflammatory, analgesic, and cardiotonic effects. Five hundred ninety-three subjects were treated with Shuchi-bushi (a powder type of this aconiti tuber that has been autoclaved) added to Kampo extract granules, between the years 1996 and 2002. The patient population consisted of 153 men and 440 women with an average age of 54.5 years. Four patients showed adverse reactions such as hypertension, nausea and hot flashes with Shuchi-bushi. There were no serious adverse effects, and the toxic symptoms disappeared quickly by reducing the Shuchi-bushi dosage, or cessation.Shuchi-bushi has been used in small quantities because of its highly toxic alkaloids. However, this study indicates that Shuchi-bushi can be used more actively.