Presumptive Iatrogenic Microcystin‐Associated Liver Failure and Encephalopathy in a Holsteiner Gelding
2016; Wiley; Volume: 30; Issue: 5 Linguagem: Inglês
10.1111/jvim.14571
ISSN1939-1676
AutoresNeil S. Mittelman, Julie B. Engiles, Lisa Murphy, Daljit Vudathala, Amy L. Johnson,
Tópico(s)Genetic and Kidney Cyst Diseases
ResumoAn 8‐year‐old Holsteiner gelding was presented for evaluation of anorexia, obtundation, icterus, and mild colic signs of 48 hours duration. History, physical examination, and initial diagnostics were suggestive of hepatic disease and encephalopathy. Microcystin toxicosis was suspected based on historical administration of a cyanobacteria supplement, associated serum biochemistry abnormalities, and characteristic histopathological changes. Microcystin contamination was confirmed in both supplement containers fed to the horse. Fulminant hepatic failure and encephalopathy progressed resulting in euthanasia. Necropsy findings were consistent with microcystin induced liver failure.
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