Produção Nacional
Revisado por pares
Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
2016; Brazilian Academy of Sciences; Volume: 88; Issue: 3 Linguagem: Inglês
10.1590/0001-3765201620150349
ISSN1678-2690
AutoresVanessa Guimarães Alves Olher, Alan G. Souza, Lucas Ulisses Rovigatti Chiavelli, Ana Lúcia Tasca Góis Ruiz, João Ernesto de Carvalho, Armando M. Pomini, Cleuza C. Silva,
Tópico(s)Phytochemistry and Bioactive Compounds
ResumoThe cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates.
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