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Molecular Rotors for the Detection of Chemical Warfare Agent Simulants

2016; American Chemical Society; Volume: 88; Issue: 18 Linguagem: Inglês

10.1021/acs.analchem.6b02516

1520-6882

Tae‐Il Kim, Shubhra Bikash Maity, Jean Bouffard, Youngmi Kim,

Molecular Sensors and Ion Detection

The fluorogenic probe o-OH is able to detect and quantify organophosphorus nerve agent mimics in solution and in the vapor phase following immobilization on a solid substrate, making the system a suitable candidate for the field detection of chemical warfare agents. Detection is achieved by the suppression of internal rotation upon phosphorylation of a reactive phenolate, resulting in a large fluorescence "turn-on" response.