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Survival and disinfection of an enveloped surrogate virus on Tyvek suits used for health care personal protective equipment

2016; Elsevier BV; Volume: 44; Issue: 12 Linguagem: Inglês

10.1016/j.ajic.2016.04.247

1527-3296

Travis W. Brown, Wei-Yu Chen, Lisa M. Casanova,

Infection Control and Ventilation

•At 6 hours, inactivation of Φ6 on Tyvek suits was 2.3 log10 at 40% relative humidity (RH) and 2.0 log10 at 60% RH. •After 1-minute contact time, there was a >3.2-log10 reduction of Φ6 on Tyvek coupons by 0.825% hypochlorite (95% confidence interval [CI], 2.59-3.82) and >4.3-log10 reduction by quaternary ammonium at the manufacturer's use dilution (95% CI, 4.22-4.44). •These results support current guidelines calling for chemical disinfection of personal protective equipment infection control measures to prevent both contamination of the wearer and the environment during removal. The survival and disinfection of bacteriophage Φ6, an enveloped surrogate virus, was evaluated on Tyvek suits used as health care personal protective equipment. After 6 hours there was 2-log10 inactivation of virus on Tyvek suits at both 40% and 60% relative humidity. Both hypochlorite and quaternary ammonium produced a >3.21- and >4.33-log10 reduction of the virus, respectively, after 1-minute contact time. Enveloped viruses can survive on Tyvek suits beyond the length of a single patient care encounter, but they can be inactivated by chemical disinfectants. The survival and disinfection of bacteriophage Φ6, an enveloped surrogate virus, was evaluated on Tyvek suits used as health care personal protective equipment. After 6 hours there was 2-log10 inactivation of virus on Tyvek suits at both 40% and 60% relative humidity. Both hypochlorite and quaternary ammonium produced a >3.21- and >4.33-log10 reduction of the virus, respectively, after 1-minute contact time. Enveloped viruses can survive on Tyvek suits beyond the length of a single patient care encounter, but they can be inactivated by chemical disinfectants.