Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes
2016; Lippincott Williams & Wilkins; Volume: 47; Issue: 9 Linguagem: Inglês
10.1161/strokeaha.116.013644
ISSN1524-4628
AutoresKennedy R. Lees, Jonathan Emberson, Lisa Blackwell, Erich Bluhmki, Stephen M. Davis, Geoffrey A. Donnan, James C. Grotta, Markku Kaste, Rüdiger von Kummer, Maarten G. Lansberg, Richard I. Lindley, Patrick D. Lyden, Gordon Murray, Peter Sandercock, Danilo Toni, Ḱazunori Toyoda, Joanna M. Wardlaw, William Whiteley, Colin Baigent, Werner Hacke, George Howard, John R. Marler, Heather Halls, Lisa Holland, Clare Mathews, Samantha Smith, Kate Wilson, Masatoshi Koga, Gregory W. Albers, Thomas Brott, Geoffrey Cohen, Masatoshi Koga, Jean‐Marc Olivot, Mark Parsons, Barbara C. Tilley, Nils Wahlgren, Gregory J. del Zoppo,
Tópico(s)Cerebrovascular and Carotid Artery Diseases
ResumoThrombolytic therapy with intravenous alteplase within 4.5 hours of ischemic stroke onset increases the overall likelihood of an excellent outcome (no, or nondisabling, symptoms). Any improvement in functional outcome distribution has value, and herein we provide an assessment of the effect of alteplase on the distribution of the functional level by treatment delay, age, and stroke severity.
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