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Melanoma central nervous system metastases: current approaches, challenges, and opportunities

2016; Wiley; Volume: 29; Issue: 6 Linguagem: Inglês

10.1111/pcmr.12538

1755-148X

Justine V. Cohen, Hussain Tawbi, Kim Margolin, Ravi Amravadi, Marcus Bosenberg, Priscilla K. Brastianos, Veronica Chiang, John de Groot, Isabella C. Glitza, Meenhard Herlyn, Sheri L. Holmen, Lucia B. Jilaveanu, Andrew B. Lassman, Stergios J. Moschos, Michael A. Postow, Reena Thomas, John A. Tsiouris, Patrick Y. Wen, Richard M. White, Timothy Turnham, Michael A. Davies, Harriet M. Kluger,

Cutaneous Melanoma Detection and Management

Summary Melanoma central nervous system metastases are increasing, and the challenges presented by this patient population remain complex. In December 2015, the Melanoma Research Foundation and the Wistar Institute hosted the First Summit on Melanoma Central Nervous System ( CNS ) Metastases in Philadelphia, Pennsylvania. Here, we provide a review of the current status of the field of melanoma brain metastasis research; identify key challenges and opportunities for improving the outcomes in patients with melanoma brain metastases; and set a framework to optimize future research in this critical area.