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BIBTEX RIS

Genomic prediction of coronary heart disease

2016; Oxford University Press; Volume: 37; Issue: 43 Linguagem: Inglês

10.1093/eurheartj/ehw450

ISSN

1522-9645

Autores

Gad Abraham, Aki S. Havulinna, Oneil G. Bhalala, Sean Byars, Alysha De Livera, Laxman Yetukuri, Emmi Tikkanen, Markus Perola, Heribert Schunkert, Eric J.G. Sijbrands, Aarno Palotie, Nilesh J. Samani, Veikko Salomaa, Samuli Ripatti, Michael Inouye,

Tópico(s)

Lipoproteins and Cardiovascular Health

Resumo

AimsGenetics plays an important role in coronary heart disease (CHD) but the clinical utility of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. Our aim was to construct and externally validate a CHD GRS, in terms of lifetime CHD risk and relative to traditional clinical risk scores.

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