Subgingival Microbiome Shifts and Community Dynamics in Periodontal Diseases
2016; California Dental Association; Volume: 44; Issue: 7 Linguagem: Inglês
10.1080/19424396.2016.12221035
ISSN1942-4396
AutoresPatricia I. Diaz, Anilei Hoare, Bo‐Young Hong,
Tópico(s)HIV/AIDS oral health manifestations
ResumoHigh-throughput 16S rRNA gene sequencing has allowed the characterization of subgingival microbiome shifts from health to periodontitis identifying health-associated, periodontitis-associated and core species, which preserve their proportions from health to disease. The development of gingivitis is also characterized by distinct shifts. Microbiome shifts resemble microbial successions and result from interspecies interactions and community adaptation to the changing environment as inflammation ensues. Gingivitis-associated and core species are proposed as likely mediators of microbiome transitions.
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