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BIBTEX RIS

Chronic hypersensitivity pneumonitis

2016; Dove Medical Press; Volume: Volume 9; Linguagem: Inglês

10.2147/jaa.s81540

1178-6965

Carlos A.C. Pereira, Andréa Gimenez, Lilian T. Kuranishi, Karin Mueller Storrer,

Occupational exposure and asthma

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are proposed for both chronic forms based on exposure, lung auscultation, lung function tests, HRCT findings, bronchoalveolar lavage, and biopsies. Treatment options are limited, but lung transplantation results in greater survival in comparison to idiopathic pulmonary fibrosis. Randomized trials with new antifibrotic agents are necessary.